The Effects of the Acidic Metabolites from the Ethanol Root Extracts Lonchocarpus Cyanecsens, Curciligo Pilosa, Securidaca Longipendiculata, Theobroma Cacao on Pseudomonas Aeruginosa

Select Volume / Issue:

• Volume 3 Issue 2, March, 2015

Year:

2015

Type of Publication:

Article

Keywords:

Acidic, Antibacterial, Extract, Metabolites, Roots

Authors:

D.C Nwokonkwo; I. Ikelle Ikelle

Journal:

IJISM

Volume:

3

Number:

2

Pages:

67-69

Month:

March

ISSN:

2347-9051

Abstract:

The effects of the acidic metabolites of the ethanol extracts of the roots of lonchocarpus cyanescens, curciligo pilosa, securidaca longipendunculata and Theobroma cacao on Pseudomonas aeruginosa was the focus of this investigation. The acidic metabolites obtained by partitioning the crude samples of the root extracts showed that the root of lonchocarpus cyanescens contained flavonoids, alkaloids, tannins, saponins, glycosides and phenols. The root of curciligo pilosa had saponins, flavonoids, alkaloids, glycosides and phenols. The acidic root extract of securidaca longipendunculata indicated the presence of tannins, flavonoids, glycosides and alkaloids. While tannins, saponins, flavonoids, alkaloids, glycosides and phenols were found in Theobroma cacao. The antibacterial screening of the extracts showed minimum inhibitory concentration (MIC) at a concentration of 100mg/mL with inhibition zone diameter (IZD) of 36 millimeter (mm) for lonchocarpus cyanescens, 00 mm for curciligo pilosa, 20 mm for securidaca longipendunculata and 30mm for Theobroma cacao. The IZD of the reference drug ampiclox at the same concentration of 100mg/mL was 25mm for lonchocarpus cyanescens 26mm for curciligo pilosa, 20mm for securidaca longipendunculata and 28mm for Theobroma cacao. Lonchocarpus cyanescens gave the highest activity at IZD of 36 mm while Curculigo pilosa gave no inhibitory activity

Full text: IJISM-346_Final.pdf [Bibtex]